In a stunning retrospective that has fans buzzing, the cast of “Grey’s Anatomy” has been revealed in a captivating “Then and Now” journey, showcasing how the beloved stars have transformed over the past two decades. This iconic series, which first graced our screens in 2005, is not just a medical drama; it’s a testament to the passage of time and the evolution of its characters and actors.

Leading the charge is Patrick Dempsey, who portrayed the charming Derek Shepherd. Now 59, Dempsey was just 39 when he first stepped into the role that would make him a household name. Meanwhile, Justin Chambers, who played the fierce Alex Karev, has aged gracefully from 34 to 54, and Chandra Wilson, the indomitable Miranda Bailey, now stands at 55 from her youthful 35.

The changes don’t stop there. James Pickens Jr. as Richard Webber has reached the milestone age of 70, while Katherine Heigl, who captivated audiences as Izzie Stevens, is now 46. The ensemble cast continues to showcase their growth, with TR Knight (George O’Malley) now at 52, and Isaiah Washington (Preston Burke) hitting 61.

As fans reflect on the journey of their favorite characters, they are also reminded of the stars who brought them to life. Ellen Pompeo, the heart of the series as Meredith Grey, is now 55, and Sandra Oh, who played Christina Yang, remains a beloved figure in the hearts of many.

This retrospective is more than just a glimpse into the past; it’s a powerful reminder of the passage of time and the enduring legacy of “Grey’s Anatomy.” As we celebrate these transformations, one thing is clear: the impact of this series is as profound today as it was when it first aired. Stay tuned as we continue to uncover more about the lives of these iconic stars!