Lionsgate has officially released the chilling first trailer for SAW XI: The Devil’s Cure, the eleventh installment in the long-running horror franchise, set for theatrical release on October 31, 2025. With Breaking Bad legend Bryan Cranston and Oscar-winning actress Penélope Cruz leading the cast, the new chapter promises to push the limits of psychological and moral terror like never before.
Scroll down to the bottom of the article to see the Trailer
🎬 Trailer Breakdown: A Deadly Serum and a Sinister Mind Game
The trailer opens with dimly lit footage of a crumbling underground clinic where whispers of failed experiments echo through rusted corridors. A chilling voiceover from Cranston’s character, Dr. Elijah Grant, sets the tone: “To save a life, sometimes you must take one.” The camera then cuts to Cruz, playing Dr. Lucia Mendez, a virologist haunted by her past, who receives a mysterious box marked with the infamous spiral symbol.
As the footage unfolds, it becomes clear this isn’t just another set of death traps. Jigsaw’s legacy has evolved — and been hijacked. A deadly virus, known only as “The Devil’s Cure,” is spreading through a secretive black-market pharmaceutical network. Victims awaken inside a facility with one mission: solve the cure or become part of the experiment.
🩸 New Direction: From Torture to Bioterror
Director Darren Lynn Bousman, returning to the franchise, revealed that SAW XI explores the ethical boundaries of modern medicine and biological warfare. “It’s no longer about just pain — it’s about choice, science, and survival. This film forces the audience to question what cure really means,” Bousman told Fangoria.
Bryan Cranston, known for his complex and morally ambiguous roles, portrays a disgraced biomedical researcher who may be pulling the strings behind the latest series of traps. Meanwhile, Penélope Cruz brings emotional depth and urgency as a mother searching for her kidnapped daughter — who may hold the key to the virus.
💉 Iconic Traps Return — With a Twist
Fans can expect a return of gruesome, intelligent traps, now fused with biotech horror. One harrowing scene teased in the trailer shows a patient having to inject a live pathogen into their own bloodstream to unlock the combination to a steel door — a countdown ticking on the walls around them.
Composer Charlie Clouser also returns to score the film, with a haunting reimagining of “Hello Zepp” featured in the trailer’s final moments.
🗓️ Official Synopsis:
“When a mysterious virus begins claiming victims around the world, a rogue scientist revives the legacy of Jigsaw in a race against time. But this time, the trap isn’t just mechanical — it’s biological. As doctors and victims alike are forced to play the game, one truth becomes clear: the cure may be deadlier than the disease.”
SAW XI: The Devil’s Cure arrives just in time for Halloween, with early fan reactions to the trailer already calling it “the boldest SAW yet.” With a star-studded cast, disturbing new traps, and a modern twist on fear, this could be the most talked-about horror release of 2025.
📽️ Watch the first official trailer now on Lionsgate’s YouTube channel.